Equine Defense Advanced Formula Shampoo

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1 Gallon, 12 oz

Item # N/A
ZYMOX® Equine Defense Advanced Formula Shampoo is used to cleanse and soothe dry, irritated skin and for the management of ringworm and rain rot. Formulated with the antimicrobial LP3 Enzyme System plus Vitamin D3 and oat extract to hydrate, nourish, and promote healthy skin.  Hypoallergenic, pH balanced, and safe for horses and livestock of all ages. Free of harsh detergents, parabens, and silicone to help keep the animal skin and coat healthy and shiny.

Made in the USA.


  • Gentle cleansing
  • Inflamed or irritated skin
  • Promotes healthy skin
  • Rain Rot
  • Ringworm
  • Sheath cleansing


  • Gentle
  • Soothing
  • Nourishing
  • Moisturizing
  • No sting
  • Tear-free
  • Won’t strip the coat
  • Pleasant smelling
  • No harsh ingredients
  • No parabens, chlorines, detergents
  • No steroids
  • Test clean

Available Sizes:  12 oz and Gallon

Manage Conditions of the Hoof and Hide

The ZYMOX Equine Defense products line utilizes the advanced technology of the patented LP3 Enzyme System for the management of chronic skin and hoof conditions. Containing no steroids, antibiotics, or petroleum by-products. 

These products are gentle and soothing to irritated skin, won’t harm surrounding healthy tissue, and don’t have the adverse effects associated with other conventional treatments.

Purified Water, PEG-80 Sorbitan Laurate, Sodium Trideceth Sulfate, Cocamidopropyl Betaine, Disodium Lauroamphodiacetate, PEG-150 Distearate, Sodium Laureth-13 Carboxylate, Sodium Chloride, Quaternium-15, Tetrasodium EDTA, DMDM Hydantoin, Citric Acid, Cocamidopropyl Hydroxysultain, Flavor, Fragrance, Cellulose Gum, Citrus Grandis (Grapefruit) Seed Extract, Avena Sativa (Oat) Extract, Zinc Gluconate, Cholecalciferol (Vitamin D3), Lysozyme, Lactoferrin, Lactoperoxidase, Potassium Iodide, Potassium Sorbate, Sorbic Acid.


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Wet animal thoroughly with water. Apply Equine Defense Shampoo directly. Work into a lather and leave on for 3 to 5 minutes then rinse completely. Repeat if needed. Follow with Equine Defense® Leave-On Conditioner for extra support of healthy skin.

  • For external use only.
  • Avoid contact with the eyes.
  • If condition worsens, consult veterinarian.
  • Keep out of reach of children.
  • Store at room temperature.

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